Why the study?
Obesity is an independent risk factor for chronic diseases, including reproductive and metabolic disorders, making its mechanisms of impacting reproductive disorders in women an important concern.
Obesity and adipose tissue play a significant role in the pathogenesis of reproductive disorders in women, including PCOS and infertility.
In recent decades, obesity has been a pressing medical and social problem for all countries, including the Russian Federation. Obesity is an independent risk factor for the development of many chronic diseases, including reproductive and metabolic disorders. The article presents data on the prevalence of obesity among women. The effect of adipose tissue on reproductive function is shown - on ovarian function, on the endometrium, as well as on the activity of the hypothalamic-pituitary-ovarian system. The relationship between obesity and polycystic ovary syndrome, infertility, and metabolic menopausal syndrome is discussed. The mechanisms of the impact of obesity on the pathogenesis of reproductive disorders in women are considered.
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Kosareva et al. (2025) studied this question.
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