Why the study?
Is the calcium-phosphorus product associated with the severity of heart valve failure in patients undergoing chronic hemodialysis?
Is the calcium-phosphorus product associated with the severity of heart valve failure in patients undergoing chronic hemodialysis?
This study found no significant association between the calcium-phosphorus product and the severity of heart valve failure in patients on chronic hemodialysis.
Does not support association in cross-sectional data; leaves open causal role of calcium-phosphorus product in hemodialysis valve failure.
BACKGROUND: Recent studies have mainly focused on the roles of serum calcium and phosphorus product in the development of valvular heart failure. We determined the association of calcium-phosphorus product with the severity of heart valve failure in patients under chronic hemodialysis (being under hemodialysis for 6 months or more) in Boo-Ali Hospital in 2012 and 2013. METHODS: It was a cross-sectional, descriptive, comparative study. Thirty-three patients undergoing chronic hemodialysis were recruited to the study. All the patients were hospitalized at Boo-Ali Hospital. The study was done in a 2 years long time frame and the association of calcium-phosphorus product and severity of heart valve failure was evaluated among them. RESULTS: The results demonstrated that there was no significant association between age, gender, renal failure cause and hemodialysis duration (P > 0.05). Our results showed a negative correlation between the severity of cardiac valves failure and CA × P level. It was not a meaningful correlation though (P > 0.05). CONCLUSIONS: Based on the obtained results, it is concluded that there is not any association between calcium-phosphorus product and the severity of heart valve failure in patients under chronic hemodialysis.
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Moshar et al. (2016) studied this question.
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