What question did this study set out to answer?

To investigate whether baseline perceived stress predicts the onset of high blood pressure and to evaluate the potential moderating effects of sex and occupational status.

July 3, 2014Journal of HypertensionOpen Access

Perceived stress, sex and occupational status interact to increase the risk of future high blood pressure

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Why the study?

Does higher perceived stress increase the risk of future high blood pressure in normotensive adults?

Key Points

To investigate whether baseline perceived stress predicts the onset of high blood pressure and to evaluate the potential moderating effects of sex and occupational status.
Prospective cohort study of 19,766 normotensive adults (13,652 men; mean age 46.8 ± 9.3 years) with no history of cardiovascular or renal disease and not taking psychotropic or antihypertensive medications.
Perceived stress was assessed at baseline using the 4-item Perceived Stress Scale, and incident high blood pressure (systolic BP ≥140 mmHg, diastolic BP ≥90 mmHg, or antihypertensive medication use) was evaluated over a mean follow-up of 5.8 ± 2.1 years.
High blood pressure occurred in 3,774 participants (19.1%), with a significant interaction between baseline perceived stress and sex (P = 0.02).
After adjustment for potential confounders, baseline perceived stress predicted incident high blood pressure in women (OR 1.20, 95% CI 1.03–1.38, P = 0.016), but showed no significant association in men.
Perceived stress and occupational status had a significant interaction among women (P = 0.02), demonstrating a linear increase in high blood pressure risk among women in medium or low occupational tiers (P = 0.005).

Structured PICO

Does higher perceived stress increase the risk of future high blood pressure in normotensive adults?

Population

19,766 normotensive adults (13,652 men), mean age 46.8 ± 9.3 years, without history of cardiovascular and renal disease, and not on either psychotropic or antihypertensive drugs.

Intervention

Baseline perceived stress measured by the 4-item Perceived Stress Scale

Outcome

High blood pressure (SBP ≥140 mmHg or DBP ≥90 mmHg, or using antihypertensive drugs) at mean 5.8 years follow-upsurrogate

Perceived stress is an independent risk factor for the development of hypertension specifically in women with lower occupational status.

Discussion

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Implication

May identify lower-status women at higher hypertension risk; hypothesis-generating and requires prospective confirmation.

Cite This Study

Wiernik et al. (2014) studied this question.

synapsesocial.com/papers/6a82a5694bc907ccd675a690 https://doi.org/10.1097/hjh.0000000000000288

Topics

Hypertension management

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Perceived stress, sex and occupational status interact to increase the risk of future high blood pressure

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Perceived stress, sex and occupational status interact to increase the risk of future high blood pressure

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider