Population
Lipid bilayer membranes with synthesized 63 residue peptide, p7, encoded by hepatitis C virus
Design
Preclinical
Authors
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Hexamethylene amiloride blocks HCV p7 channels in animal models; leaves open antiviral translation to humans.
Hexamethylene amiloride blocks p7 ion channels of hepatitis C virus, suggesting a potential target for antiviral agents.
Premkumar et al. (2003) studied this question.
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