Why the study?
Appendicitis is the most common and frequently misdiagnosed acute abdominal surgical illness in paediatric patients, prompting evaluation of the coagulation profile's role in children with acute appendicitis.
Does the coagulation profile correlate with the severity of acute appendicitis in pediatric patients?
Population
Paediatric patients submitted to appendectomy from 2011 to 2017
Comparison
Not histologically confirmed AA vs simple AA vs complicated AA
Design
Retrospective study
Authors
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Fibrinogen may aid severity assessment in pediatric appendicitis; leaves open its diagnostic utility pending prospective validation.
Does the coagulation profile correlate with the severity of acute appendicitis in pediatric patients?
The extrinsic coagulation pathway, particularly fibrinogen, is altered in acute appendicitis and may be useful in the diagnostic and perioperative management of children.
Franzini et al. (2020) studied this question.
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