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July 1, 1978British journal of surgery

Thrombus was demonstrated in 49.4% of suspected DVT patients and 53% of suspected PE patients; among 535 limbs with thrombus, 92% had calf involvement (isolated or continuous proximally) and 8% had isolated proximal or discontinuous thrombi.

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Why the study?

What is the anatomical distribution and origin of deep vein thrombi in patients with suspected DVT or PE?

Population

952 patients examined by ascending venography, including 812 with clinically diagnosed deep vein thrombosis…

Design

Cross-sectional

Authors

JSJ D StamatakisVKV V KakkarDLDavid Lawrence

Discussion

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Overview

Supports calf-origin hypothesis for most DVT; hypothesis-generating for imaging protocols pending prospective validation.

Structured PICO

What is the anatomical distribution and origin of deep vein thrombi in patients with suspected DVT or PE?

P
Population
952 patients examined by ascending venography, including 812 with clinically diagnosed deep vein thrombosis (DVT) and 140 with clinical features suggestive of pulmonary embolism (PE).
I
Intervention
Ascending venography
O
Outcome
Presence and anatomical location of thrombus in the deep veins of the lower limbsurrogate

The vast majority (92%) of lower limb deep vein thrombi involve the calf veins, suggesting that most DVT originates in the calf before propagating proximally.

Cite This Study

Stamatakis et al. (1978) studied this question.

synapsesocial.com/papers/6a82a7c5aab30c8fb7b283echttps://doi.org/10.1002/bjs.1800650702
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