The study provides a mathematical model for Hand-Foot-Mouth disease transmission dynamics and identifies optimal control strategies for treatment and vaccination.
Model-derived HFMD controls merit exploration; leaves open empirical validation before clinical use.
In this article, the transmission dynamics of a Hand-Foot-Mouth disease model with treatment and vaccination interventions are studied. We calculated the basic reproduction number and proved the global stability of disease-free equilibrium when R0 R0 > 1. Meanwhile, we obtained the optimal control strategies minimizing the cost of intervention and minimizing the infected person. We also give some numerical simulations to verify our theoretical results.
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Wang et al. (2024) studied this question.
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