Why the study?
The prevalence of meningitis and encephalitis of unknown aetiology in Spanish children had not been specifically documented before.
Undiagnosed central nervous system entities remain a significant cause of paediatric hospitalisations in Spain, though incidence declined from 2016 to 2020.
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Undiagnosed CNS entities remain a significant cause of pediatric hospitalizations in Spain; hypothesis-generating for etiology and prevention strategies.
Pons‐Espinal et al. (2025) studied this question.
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