What question did this study set out to answer?

To examine international differences in premature mortality patterns among population-based cohorts of individuals diagnosed with youth-onset insulin-dependent diabetes mellitus.

January 1, 1991Diabetes Care

Major Cross-Country Differences in Risk of Dying for People With IDDM

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Implication

Multinational cohort study reveals substantial cross-country differences in premature mortality among youth-onset diabetes cohorts, highlighting disproportionately high death rates in the US and...

Key Points

To examine international differences in premature mortality patterns among population-based cohorts of individuals diagnosed with youth-onset insulin-dependent diabetes mellitus.
Analyzed four population-based cohorts of youth-onset IDDM (diagnosed <18 years of age and prescribed insulin at discharge between January 1, 1965, and December 31, 1979) in Allegheny County, Pennsylvania (n=1,000), Finland (n=5,146), Israel (n=681), and Japan (n=1,428).
Determined vital status as of January 1, 1985, using life-table analyses and standardized age-adjusted mortality rates per 100,000 person-years of diabetes to facilitate cross-country comparisons.
At 20 years of diabetes duration, cumulative mortality reached 5.5% in Allegheny County compared to 4.6% in Israel and 3.1% in Finland (P < 0.01).
Extended 3-year follow-up among individuals aged 30 to 39 years showed 3.9 times greater premature mortality in the United States cohort compared with the Finnish cohort (2.3% vs. 0.6%).
Direct comparison across reconfigured cohorts showed markedly higher age-adjusted mortality rates in Japan (681 per 100,000 person-years) relative to the United States (230), Finland (171), and Israel (131).

Cite This Study

A 1991 study studied this question.

synapsesocial.com/papers/6a82aa559192075d3cd4ae49 https://doi.org/10.2337/diacare.14.1.49

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Implication

Multinational cohort study reveals substantial cross-country differences in premature mortality among youth-onset diabetes cohorts, highlighting disproportionately high death rates in the US and...

Major Cross-Country Differences in Risk of Dying for People With IDDM

Discussion

Member takes

Implication

Key Points

Cite This Study

Major Cross-Country Differences in Risk of Dying for People With IDDM

Discussion

Member takes

Implication

Key Points

Cite This Study

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