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March 2, 1988European Heart Journal

Significant spasm was induced in 7 patients (22%), and 6 of these 7 patients complained of atypical chest pain compared to 2 of 25 patients with a negative test (P < 0.01).

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Why the study?

Does an ergonovine test induce coronary artery spasm in patients with atypical chest pain after successful PTCA?

Population

32 consecutive patients showing a good long-term result 3 to 6 months after successful PTCA

Design

Cohort

Follow-up

3 to 6 months after PTCA

Authors

PPPeter ProbstWZWalheide ZanglCBChristian Baumgärtner

Discussion

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Overview

Spasm induction associated with atypical pain post-PTCA; hypothesis-generating and should not yet change practice.

Structured PICO

Does an ergonovine test induce coronary artery spasm in patients with atypical chest pain after successful PTCA?

P
Population
32 consecutive patients showing a good long-term result 3 to 6 months after successful PTCA
I
Intervention
Ergonovine test (0.2 mg ergonovine i.v.)
O
Outcome
Inducibility of significant coronary artery spasmsurrogate

Coronary artery spasm can be induced in a significant proportion of patients with atypical chest pain after successful PTCA, suggesting increased vasomotor tone at the previous stenosis site.

Cite This Study

Probst et al. (1988) studied this question.

synapsesocial.com/papers/6a82aaf4ac779081c023b429https://doi.org/10.1093/eurheartj/9.suppl_c.19
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