Why the study?
Does a provocative test with ergometrine induce coronary spasm in patients with recent transmural myocardial infarction?
Population
131 patients (124 men and 7 women) with recent (less than 6 weeks) transmural myocardial infarction.
Design
Cross-sectional
Follow-up
5 minutes post-provocation
Authors
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Suggests coronary spasm may contribute to post-MI ischemia; hypothesis-generating and leaves open routine testing or targeted therapy.
Does a provocative test with ergometrine induce coronary spasm in patients with recent transmural myocardial infarction?
A high degree of coronary reactivity is present in patients with recent transmural myocardial infarction, suggesting coronary spasm may play a role in the infarction process and recurrent ischemia.
Bertrand et al. (1983) studied this question.
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