Why the study?
Does the addition of adrenaline and fentanyl to bupivacaine improve epidural analgesia in healthy women with uncomplicated pregnancies?
Population
90 healthy Chinese women with uncomplicated pregnancies
Comparison
10 ml epidural solutions containing bupivacaine… vs 10 ml bupivacaine 0.125% or 0.25% plain
Design
RCT, randomly allocated, double-blind
Authors
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Adrenaline addition to epidural bupivacaine speeds onset and prolongs labor analgesia; supports routine adjuvant use and further optimization trials.
Does the addition of adrenaline and fentanyl to bupivacaine improve epidural analgesia in healthy women with uncomplicated pregnancies?
A low-concentration mixture of bupivacaine 0.125% with adrenaline and fentanyl provides effective obstetric epidural analgesia.
YAU et al. (1990) studied this question.
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