Why the study?
Does bupivacaine 0.125% with epinephrine provide satisfactory epidural analgesia with minimal motor paralysis in women in labor?
Population
3,000 women in labor
Design
Cohort
Follow-up
Duration of labor and delivery
Authors
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May support low-dose bupivacaine-epinephrine epidurals for labor; hypothesis-generating and requires randomized confirmation before practice change.
Does bupivacaine 0.125% with epinephrine provide satisfactory epidural analgesia with minimal motor paralysis in women in labor?
Bupivacaine 0.125% with epinephrine provides highly effective obstetric epidural analgesia with minimal motor blockade and an excellent safety profile.
Bleyaert et al. (1979) studied this question.
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