Why the study?
Does adding epinephrine to epidural bupivacaine improve analgesia in healthy parturients during labor?
Population
100 healthy parturients during labor
Comparison
10 ml of 0.25% bupivacaine with 1:300,000… vs 10 ml of 0.25% plain bupivacaine epidurally
Design
RCT, random manner
Authors
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Supports epinephrine addition to epidural bupivacaine for labor analgesia; confirms benefit in healthy parturients without added hypotension.
Does adding epinephrine to epidural bupivacaine improve analgesia in healthy parturients during labor?
Adding 1:300,000 epinephrine to 0.25% epidural bupivacaine modestly but significantly improves analgesic efficacy during labor without increasing hypotension.
Eisenach et al. (1987) studied this question.
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