Key result
Coronary artery bypass grafting was associated with a significantly lower risk of long-term cardiac death, revascularization, and MACCE compared with PCI in patients with NSTE-ACS and 3-vessel CAD.
Why the study?
What is the most preferable treatment strategy for patients with NSTE-ACS with multivessel disease?
What is the most preferable treatment strategy for patients with NSTE-ACS with multivessel disease?
Answers are grounded in this paper and cite their sources.
The author highlights the need for large-scale real-world registries to collect long-term outcome data for patients with NSTE-ACS and multivessel disease.
fore, long-term outcome data of this high-risk patient group should be collected in large-scale real-world registries.In this issue of the Journal, Jia et al 7 report the long-term clinical outcomes of patients with NSTE-ACS and 3-vessel disease who underwent PCI, CABG, or medical therapy alone in a large-scale single-center database.Their study showed that CABG was significantly associated with a lower risk of long-term cardiac death, revascularization, C urrent guidelines recommend coronary artery bypass grafting (CABG) over percutaneous coronary intervention (PCI) for patients with left main or multivessel coronary artery disease (CAD). 1 However, data are lacking regarding long-term clinical outcomes in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) who undergo CABG, PCI, or medical therapy alone.2-5 The optimal management strategy for these patients in terms of the long-term (especially >5 years) clinical outcomes is still debatable because of the lack of randomized controlled trials regarding this issue.
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Yohei Numasawa (2020) conducted an editorial in Non-ST-elevation acute coronary syndrome (NSTE-ACS) with 3-vessel coronary artery disease (n=3,928). Coronary artery bypass grafting (CABG) vs. Percutaneous coronary intervention (PCI) or medical therapy alone was evaluated on Long-term cardiac death, revascularization, and major adverse cardiac and cerebrovascular events (MACCE). Coronary artery bypass grafting was associated with a significantly lower risk of long-term cardiac death, revascularization, and MACCE compared with PCI in patients with NSTE-ACS and 3-vessel CAD.
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