Pharmacist-Led Interventions for Type 2 Diabetes Mellitus : A Systematic Review

Background: Pharmacists can also contribute positively to diabetes management.The aim of this study to explore pharmacist interventions in the management of T2DM.Methods: Article review was search of Pubmed, Embase and Science Direct during the period 2009-2019.A Combination of keys terms such as "pharmacists", "intervention", "type 2 diabetes mellitus" was used for the search.Trials were included if they were published in the English, evaluated any form of pharmacist interventions in the management of T2DM.Results: There were 9 articles included and the studies evaluated the impact of several pharmacist interventions carried out in various countries and in community pharmacies.Pharmacist-led interventions had a positive effect on A1c with the difference in change between groups ranging from -0.3% to -1.0%; blood glucose (-1.43 mg/dL to -44 mg/dL); SBP (+0.6 mmHg to -23 mmHg); DBP (+1.3 mmHg to -22.3 mmHg); LDL (+0.18 mg/dL to -17.5 mg/dL); HDL (+0.31 mg/dL to +6.4 mg/dL); total cholesterol (+0,49 mg/dL to -7,5 mg/dL); triglycerides (-0.3 mg/dL to -28.3 mg/dL).A beneficial effect on BMI was also described in the intervention group.Pharmacist interventions had a positive impact on medication adherence and HRQoL in most studies.Conclusion: Pharmacist interventions can have a positive influence on metabolic control, medication adherence and HRQoL of patients with T2DM.