Why the study?
Does desflurane anesthesia increase perioperative myocardial ischemia compared to sufentanil in patients undergoing CABG surgery?
Population
200 patients with known coronary artery disease undergoing coronary artery bypass graft (CABG) surgery
Comparison
Desflurane (thiopental adjuvant) anesthesia vs Sufentanil anesthesia
Design
RCT, randomly assigned
Follow-up
Perioperative period
Authors
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Avoid desflurane for induction in CABG due to higher ischemia rates; challenges assumptions of hemodynamic equivalence to sufentanil.
Does desflurane anesthesia increase perioperative myocardial ischemia compared to sufentanil in patients undergoing CABG surgery?
Desflurane anesthesia is associated with a higher risk of hemodynamic instability and ECG-detected myocardial ischemia during anesthetic induction compared to sufentanil in patients undergoing CABG.
Helman et al. (1992) studied this question.
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