Why the study?
Does sevoflurane reduce myocardial ischemia and adverse cardiac outcomes compared to isoflurane in adults with cardiac disease undergoing noncardiac surgery?
Population
214 adults (40-87 years) with cardiac disease undergoing elective noncardiac surgery
Comparison
Sevoflurane in conjunction with sodium… vs Isoflurane in conjunction with sodium…
Design
RCT, randomized
Follow-up
48 hours postoperatively
Authors
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Sevoflurane offers no cardiac outcome advantage over isoflurane; confirms their equivalence in adults with cardiac disease undergoing noncardiac surgery.
Does sevoflurane reduce myocardial ischemia and adverse cardiac outcomes compared to isoflurane in adults with cardiac disease undergoing noncardiac surgery?
In adults with cardiac disease undergoing noncardiac surgery, sevoflurane and isoflurane are associated with a similar incidence of perioperative myocardial ischemia and adverse cardiac outcomes.
Ebert et al. (1997) studied this question.
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