What question did this study set out to answer?

To evaluate the feasibility, precision, and reproducibility of three-dimensional ultrasound angiography for quantifying carotid artery plaque volume and surface characteristics in cerebrovascular disease.

January 1, 1997Journal of Neuroimaging

Three‐dimensional Ultrasound Angiography (Power Mode) for the Quantification of Carotid Artery Atherosclerosis

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Why the study?

Does 3D ultrasound angiography provide reliable quantification and differentiation of carotid artery atherosclerosis compared to conventional Doppler ultrasound in patients with cerebrovascular disease?

Population

35 patients (15 women, 20 men) with a history of cerebrovascular disease

Comparison

Three-dimensional (3D) ultrasound angiography vs Conventional color-coded Doppler ultrasound and…

Design

Cross-sectional

Authors

BGB. GriewingRhön-Klinikum USUlf SchminkeVascular Medicine CMChristoph MorgensternUniversitätsmedizin Greifswald

Discussion

Member takes

Implication

Supports 3D ultrasound reproducibility for carotid plaque assessment; leaves open validation versus Doppler in cerebrovascular disease.

Key Points

To evaluate the feasibility, precision, and reproducibility of three-dimensional ultrasound angiography for quantifying carotid artery plaque volume and surface characteristics in cerebrovascular disease.
Examined 35 patients (15 women, 20 men) with a history of cerebrovascular disease using conventional color-coded Doppler ultrasound and 3D ultrasound angiography.
Evaluated intraobserver and interobserver reliabilities in a subset of 21 patients scanned on three separate occasions.
Recorded scanning acquisition time (5 minutes per patient) and offline reconstruction and plaque volume quantification time (30 minutes).
Carotid stenosis exceeded 50% in 65% of patients, with plaque morphology characterized as ulcerated in 72.9%, smooth in 22.0%, and indeterminate in 5.1%.
Plaque volumes ranged from 0.053 to 0.685 ml, with intraobserver variability of 4.16% (r = 0.96, p < 0.0001) and interobserver variability of 5.87% (r = 0.89, p < 0.0001).
Plaque volume estimates differed by 8.5% between 3D color Doppler and 3D ultrasound angiography, with 3D reconstruction showing reduced artifact from acoustic shadowing.

Structured PICO

Population

35 patients (15 women, 20 men) with a history of cerebrovascular disease

Intervention

Three-dimensional (3D) ultrasound angiography

Comparator

Conventional color-coded Doppler ultrasound and continuous-wave Doppler ultrasound

Outcome

Intraobserver and interobserver reliabilities for plaque volume quantificationsurrogate

3D ultrasound angiography provides a highly reproducible method for quantifying carotid plaque volume with low intra- and interobserver variability, offering a precise tool for clinical studies.

Cite This Study

Griewing et al. (1997) studied this question.

synapsesocial.com/papers/6a82c00aaa66c98ddba0cec2 https://doi.org/10.1111/jon19977140

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Three‐dimensional Ultrasound Angiography (Power Mode) for the Quantification of Carotid Artery Atherosclerosis

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Three‐dimensional Ultrasound Angiography (Power Mode) for the Quantification of Carotid Artery Atherosclerosis

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider