Why the study?
Is PvuII RFLP associated with familial lipoprotein lipase deficiency in Japanese patients?
Population
8 familial lipoprotein lipase (LPL)-deficient patients and 50 unrelated controls, Japanese
Comparison
PvuII restriction fragment length polymorphism… vs Unrelated controls
Design
Case-control
Authors
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PvuII A1 homozygosity was associated with LPL deficiency in this small Japanese case-control study; leaves open its value as a genetic marker pending larger validation.
Is PvuII RFLP associated with familial lipoprotein lipase deficiency in Japanese patients?
The PvuII RFLP A1 homozygote genotype is strongly associated with familial lipoprotein lipase deficiency in Japanese patients, serving as a useful genetic marker.
Gotoda et al. (1989) studied this question.
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