Why the study?
How should a 45-year-old man with hypertriglyceridemia (fasting triglyceride level of 400 mg/dL) be assessed and managed?
How should a 45-year-old man with hypertriglyceridemia (fasting triglyceride level of 400 mg/dL) be assessed and managed?
This clinical vignette introduces a discussion on the assessment and management of moderate hypertriglyceridemia in an otherwise healthy adult.
Offers no new evidence to guide moderate hypertriglyceridemia management; leaves open optimal strategies for prospective trials.
A healthy 45-year-old man is found on routine screening to have hypertriglyceridemia. He does not have diabetes, and he takes no medications. His father died at 55 years of age in an automobile accident, his mother is healthy at the age of 67 years, and he has two healthy older brothers. His body-mass index is 28. His fasting triglyceride level is 400 mg per deciliter, total cholesterol 230 mg per deciliter, LDL cholesterol 120 mg per deciliter, and HDL cholesterol 30 mg per deciliter. How should his case be assessed and managed?
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A 2007 study studied this question.
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