Why the study?
Does paracervical block with mepivacaine cause fetal bradycardia due to drug toxicity?
Population
Women in labor and their fetuses
Design
Cohort
Authors
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May warrant caution with mepivacaine paracervical block; hypothesis-generating for toxicity link, needs randomized confirmation.
Does paracervical block with mepivacaine cause fetal bradycardia due to drug toxicity?
Fetal bradycardia following paracervical block is associated with mepivacaine toxicity via placental transfer, highlighting that this anesthesia is contraindicated when placental insufficiency is anticipated.
Howard R. Gordon (1968) studied this question.
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