Why the study?
Does COMP-Ang1 protect against radiation-induced bone marrow damage in C57BL/6 mice?
Population
C57BL/6 mice exposed to ionizing radiation (4.5 Gy whole body radiation)
Design
Preclinical
Authors
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May support COMP-Ang1 development for radiation protection; hypothesis-generating and should not yet change practice.
Does COMP-Ang1 protect against radiation-induced bone marrow damage in C57BL/6 mice?
COMP-Ang1 gene transfer protects bone marrow from radiation-induced damage in a mouse model, suggesting its potential as an alternative to native Ang1 for therapeutic purposes.
Lee et al. (2008) studied this question.
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