Why the study?
The study aimed to determine the prevalence of hypertension, recommended therapy, and BP target achievement in an Iranian population according to 2017 ACC/AHA versus JNC7 and 8 guidelines.
How do the 2017 ACC/AHA hypertension guidelines compare to JNC7 and JNC8 in determining hypertension prevalence, treatment recommendations, and target achievement in an Iranian population?
How do the 2017 ACC/AHA hypertension guidelines compare to JNC7 and JNC8 in determining hypertension prevalence, treatment recommendations, and target achievement in an Iranian population?
The 2017 ACC/AHA guidelines substantially increase the prevalence of hypertension compared to JNC7/8, but most newly diagnosed patients are at low cardiovascular risk.
Should not yet change practice in low-risk groups; leaves open whether ACC/AHA thresholds improve outcomes versus prior guidelines.
This study aimed to determine the prevalence of hypertension, the recommended anti-hypertensive therapy and the percentage of hypertensive patients who had achieved the blood pressure (BP) target according to 2017 American College of Cardiology/American Heart Association (ACC/AHA) versus JNC7 and 8 guidelines, among Iranian population. Data of participants aged ≥20 years from the fifth phase (2012-2015) of the Tehran lipid and glucose study (N = 10,576) were analyzed, using survey analysis. The weighted prevalence of hypertension among those not on anti-hypertensive medications was 42.7 and 12.6%, applying the ACC/AHA and JNC7 guideline definitions, respectively; the corresponding values with including BP-lowering medication in definition of hypertension were 47.1% and 20.4%, respectively. However, 90% of these hypertensive people were found to have a 10-year cardiovascular disease risk of <10%. Applying the ACC/AHA guideline, anti-hypertensive medication was recommended for 21.9% of Tehranians, compared to 19.3 and 12.2% according to the JNC7 and 8 guidelines, respectively. Among Tehranians taking anti-hypertensive medication, 20% achieved the BP goal according to the ACC/AHA guideline, compared to the 42.1 and 53.6%, using JNC7 and 8 guidelines, respectively. Despite the tremendous increase in the prevalence of hypertension, most of the newly identified cases did not belong to the high-risk group.
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Asgari et al. (2019) studied this question.
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