Population
Pig coronary artery smooth muscle
Comparison
Varying pH levels and substrate concentrations vs Different pH levels and different subcellular…
Design
Preclinical
Authors
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Differential ATP/pH sensitivities distinguish PM vs ER Ca pumps in porcine coronary smooth muscle; hypothesis-generating for vascular Ca homeostasis, human studies needed.
In pig coronary artery smooth muscle, the endoplasmic reticulum calcium pump may play a larger role in vasodilation, whereas the plasma membrane pump is more involved in maintaining relaxation.
Grover et al. (1986) studied this question.
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