Why the study?
Does bacillus Calmette-Guérin (BCG) or TLR4 agonist prevent cardiovascular hypertrophy and fibrosis in murine models of hypertension?
Does bacillus Calmette-Guérin (BCG) or TLR4 agonist prevent cardiovascular hypertrophy and fibrosis in murine models of hypertension?
BCG and TLR4 agonists prevent hypertension-induced cardiovascular hypertrophy and fibrosis by regulating the immune microenvironment and TLR4 signaling pathways in a murine model.
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May attenuate hypertensive cardiac remodeling in mice; leaves open translation to human disease.
Liu et al. (2008) studied this question.
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