Why the study?
Does discrete stimulation of carotid chemoreceptors increase plasma ANP levels in anaesthetized dogs?
Population
Seven chloralose-anaesthetized and artificially ventilated beagles with vascularly isolated carotid sinus…
Comparison
Stimulation of carotid chemoreceptors for 25… vs Baseline/perfusion with arterial blood.
Design
Preclinical
Follow-up
25 minutes
Authors
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Does not alter clinical practice; leaves open chemoreflex-ANP pathways in human cardiorespiratory disease.
Does discrete stimulation of carotid chemoreceptors increase plasma ANP levels in anaesthetized dogs?
Discrete stimulation of carotid chemoreceptors causes an increase in plasma ANP levels, likely mediated by reflex increases in atrial pressure.
Al-Obaidi et al. (1991) studied this question.
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