Why the study?
Does surgical denervation of aortic chemoreceptors alter the cardiac and respiratory responses to acute hypoxia in anesthetized dogs?
Population
Anesthetized dogs (morphine-pentobarbital)
Comparison
Surgical denervation of the aortic… vs Sham-operated dogs exposed to the same 15 min…
Design
Preclinical
Follow-up
15 minutes
Authors
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Supports aortic chemoreceptor contribution to hypoxic cardiac responses in dogs; leaves open translation to human physiology and clinical practice.
Does surgical denervation of aortic chemoreceptors alter the cardiac and respiratory responses to acute hypoxia in anesthetized dogs?
Aortic chemoreceptors play a significant role in the cardiac response to hypoxia but do not significantly affect the respiratory response in anesthetized dogs.
Biro et al. (1973) studied this question.
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