Why the study?
Does aortic chemoreceptor denervation alter the circulatory and metabolic responses to acute anemia in dogs?
Population
16 anesthetized dogs (n=9 with surgically denervated aortic chemoreceptors, n=7 sham-operated)
Comparison
Acute anemia produced by isovolemic… vs Sham-operated dogs undergoing the same acute…
Design
Preclinical
Follow-up
30 minutes
Authors
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Aortic chemoreceptors may aid anemia compensation in dogs; hypothesis-generating and should not change practice.
Does aortic chemoreceptor denervation alter the circulatory and metabolic responses to acute anemia in dogs?
Aortic chemoreceptors contribute significantly to the compensatory increase in cardiac output during acute anemia.
Szlyk et al. (1984) studied this question.
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