Key result
Implementation of the Mayo Clinic STEMI protocol significantly reduced median door-to-balloon time from 97 to 67 minutes and increased the proportion achieving <90 minutes from 40% to 81% (P<0.001).
Why the study?
Does a standardized STEMI protocol reduce door-to-balloon time in nontransferred STEMI patients undergoing primary PCI?
Population
418 nontransferred patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary…
Comparison
Mayo Clinic STEMI protocol. vs Preimplementation standard of care.
Design
Cohort
Follow-up
4 years
Authors
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May support local STEMI protocol adoption to shorten reperfusion; leaves open generalizability and multicenter validation.
Observational (n=418)
No
Does a standardized STEMI protocol reduce door-to-balloon time in nontransferred STEMI patients undergoing primary PCI?
Absolute Event Rate: 81% vs 40%
p-value: p=<0.001
Implementation of a comprehensive STEMI protocol significantly reduces door-to-balloon times, with improvements sustained over a 4-year period.
Nestler et al. (2009) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=418). Mayo Clinic STEMI protocol vs. Preimplementation standard of care was evaluated on Door-to-balloon time <90 minutes (p=<0.001). Implementation of the Mayo Clinic STEMI protocol significantly reduced median door-to-balloon time from 97 to 67 minutes and increased the proportion achieving <90 minutes from 40% to 81% (P<0.001).
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