Key result
The CODE STEMI notification system significantly reduced median door-to-balloon time (45.0 vs 67.1 min, P=0.001) and increased the proportion of patients achieving ≤90 min (95.2% vs 73.2%, P=0.007).
Why the study?
Does an ED physician-activated STEMI notification system reduce door-to-balloon time in STEMI patients undergoing primary PCI?
Cohort (n=83)
No
Does an ED physician-activated STEMI notification system reduce door-to-balloon time in STEMI patients undergoing primary PCI?
Absolute Event Rate: 95.2% vs 73.2%
p-value: p=0.007
Implementation of an ED physician-activated STEMI notification system significantly reduces door-to-balloon time and increases the proportion of patients meeting the ≤90 minute target.
OBJECTIVE: Reducing time to reperfusion for ST-segment elevation myocardial infarction (STEMI) is essential in improving outcomes. Consequently, numerous strategies have been employed to reduce median door-to-balloon time (DTBT). METHODS: CODE STEMI is an ED physician-activated STEMI notification system. On activation, an announcement is made over the hospital's public announcement (PA) system. We prospectively analysed all in-hours STEMI patients who had primary percutaneous coronary intervention (PPCI) Pre-CODE STEMI (2014) and after CODE STEMI was implemented (2015). The primary end-points were median DTBT and the proportion of STEMI patients achieving a DTBT ≤90 min. The secondary end-points were in-hospital outcomes, and a composite of major adverse cardiac events (MACE) and hospital readmission rates at 30 days and 12 months. RESULTS: There were 41 and 42 patients in Pre-CODE STEMI and CODE STEMI groups respectively. Baseline characteristics were similar. DTBT was significantly reduced by 22.1 min from 67.1 ± 34.9 min Pre-CODE STEMI to 45.0 ± 22.7 min (P = 0.001) in the CODE STEMI group. Door-to-door time (DTDT) was also reduced from 46.3 ± 30.9 min to 29.4 ± 23.3 min (P = 0.006). A greater proportion of CODE STEMI patients achieved the target DTBT ≤90 min (95.2% vs 73.2%, P = 0.007). CODE STEMI patients had less systolic dysfunction measured by a left ventricle ejection fraction of ≤40% (10.0% vs 27.8%, P = 0.07). There were trends to lower in-hospital mortality rates (4.8% vs 9.8%, P = 0.43), MACE at 30 days and 12 months (4.8% vs 9.8%, P = 0.43; 11.9% vs 22.0%, P = 0.25). CONCLUSION: The novel in-hospital in-hours CODE STEMI notification system significantly reduced DTBT in patients undergoing PPCI.
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Koh et al. (2017) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=83). CODE STEMI notification system vs. Pre-CODE STEMI was evaluated on proportion of STEMI patients achieving a DTBT ≤90 min (p=0.007). The CODE STEMI notification system significantly reduced median door-to-balloon time (45.0 vs 67.1 min, P=0.001) and increased the proportion of patients achieving ≤90 min (95.2% vs 73.2%, P=0.007).
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