Key result
Interaction between premature ventricular contraction timing and implantable cardioverter-defibrillator blanking periods caused recurrent polymorphic ventricular tachycardia/fibrillation in 2 patients.
Why the study?
ICDs and biventricular ICDs can be proarrhythmic, particularly when pacing into scar tissue.
Population
2 patients with frequent PVCs and ICDs developing recurrent polymorphic VT/VF
Design
Case series
Authors
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May prompt consideration of PVC-ICD timing in recurrent VT/VF; hypothesis-generating case report leaves optimal programming strategies open.
Case Report (n=2)
Highlights a proarrhythmic mechanism in ICD patients where frequent PVCs interact with device blanking periods, causing R-on-T pacing and subsequent VT/VF.
H. et al. (2020) conducted a case report in Cardiomyopathy with frequent premature ventricular contractions and implantable cardioverter-defibrillators (n=2). Implantable cardioverter-defibrillators (ICD) was evaluated on Recurrent polymorphic ventricular tachycardia/fibrillation. Interaction between premature ventricular contraction timing and implantable cardioverter-defibrillator blanking periods caused recurrent polymorphic ventricular tachycardia/fibrillation in 2 patients.