Key result
Aspirin showed no difference in rates of venous thrombo-embolism compared to low molecular weight heparin following total knee arthroplasty based on one good quality randomized controlled trial.
Why the study?
Does aspirin prevent venous thrombo-embolism as effectively as other chemoprophylactic agents in patients undergoing elective total hip and knee arthroplasty?
Systematic Review
Does aspirin prevent venous thrombo-embolism as effectively as other chemoprophylactic agents in patients undergoing elective total hip and knee arthroplasty?
Aspirin may be a suitable alternative to other thromboprophylactic agents following total hip and knee arthroplasty, though further investigation is required.
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Aspirin may be a suitable alternative to LMWH after TKA; leaves open need for larger confirmatory trials.
Wilson et al. (2016) conducted a systematic review in Total hip and knee arthroplasty. Aspirin vs. LMWH, warfarin, dabigatran, or rivaroxaban was evaluated on Venous thrombo-embolism (VTE). Aspirin showed no difference in rates of venous thrombo-embolism compared to low molecular weight heparin following total knee arthroplasty based on one good quality randomized controlled trial.
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