Key result
Among patients on warfarin therapy, 62% had poor anticoagulation control (TTR <50%), with male gender and employment identified as significant predictors for good INR control.
Why the study?
Warfarin remains widely prescribed and cannot be substituted in certain indications, prompting the need to assess factors associated with INR control.
What factors are associated with good International Normalized Ratio (INR) control in patients receiving warfarin therapy?
Population
250 patients on warfarin therapy for different indications
Design
Retrospective cohort study
Authors
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Frequent poor TTR on warfarin warrants vigilant monitoring; leaves open whether targeting predictors improves outcomes.
Cohort (n=250)
No
What factors are associated with good International Normalized Ratio (INR) control in patients receiving warfarin therapy?
The majority of patients on warfarin therapy demonstrated poor anticoagulation control, highlighting the ongoing challenge of warfarin management and the potential need for closer monitoring in specific demographic groups.
Al‐Shaer et al. (2020) conducted a cohort in Patients receiving warfarin therapy (n=250). Patient factors (gender, education, employment) was evaluated on Poor anticoagulation control (Time in Therapeutic Range <50%). Among patients on warfarin therapy, 62% had poor anticoagulation control (TTR <50%), with male gender and employment identified as significant predictors for good INR control.
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