Key result
PAH-directed therapy and supportive treatment strategies are important for the palliation of symptoms in patients with advanced pulmonary arterial hypertension.
This review highlights the importance of balancing PAH-directed therapies and supportive treatments to palliate symptoms and manage treatment burden in advanced PAH.
Supports symptom palliation with PAH-directed and supportive therapies in advanced PAH; leaves open optimal balancing for prospective studies.
Pulmonary arterial hypertension (PAH) is a complex disease in which the illness as well as the associated treatment can be particularly burdensome. Previously considered to be uniformly fatal, PAH treatment and management has improved with an extended survival. However, this can come with symptom burden. Burden can be associated with the disease itself in addition to the treatment aimed at ameliorating these symptoms. This article explores both the use of PAH-directed therapy as well as traditionally supportive treatment strategies for palliation of symptoms in those with PAH. As highlighted in the patient case described throughout this issue, patients are constantly weighing the benefits and burdens of treatment during each step of their journey.
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Malotte et al. (2018) conducted a review in Advanced Pulmonary Arterial Hypertension. PAH-directed therapy and supportive treatment strategies was evaluated. PAH-directed therapy and supportive treatment strategies are important for the palliation of symptoms in patients with advanced pulmonary arterial hypertension.
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