Key result
In rat experimental autoimmune myocarditis, most immunological molecules are expressed in inflammatory cells, while IL-10, MCP-1, TNF-alpha receptor, and fractalkine are found in NCNI cells and cardiomyocytes.
Authors
Loading...
No direct clinical implications from rat model; leaves open validation of NCNI/cardiomyocyte roles in human myocarditis.
Yoshida et al. (2005) studied Experimental autoimmune myocarditis. Experimental autoimmune myocarditis (EAM) immunization vs. Normal rats was evaluated on Native gene expression of immunological molecules. In rat experimental autoimmune myocarditis, most immunological molecules are expressed in inflammatory cells, while IL-10, MCP-1, TNF-alpha receptor, and fractalkine are found in NCNI cells and cardiomyocytes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: