Population
Bovine viral diarrhea virus in vitro models
Comparison
Compound-1453 vs Wild-type virus vs resistant virus, or absence…
Design
Preclinical
Authors
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May inform lead optimization but should not change practice; leaves open in vivo efficacy and clinical translation.
Compound-1453 is identified as a specific, novel inhibitor of the bovine viral diarrhea virus RNA-dependent RNA replicase.
Sun et al. (2003) studied this question.
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