Key result
The COVID-19 epidemic was associated with a higher rate of AMI patients refusing hospitalization (5.0% vs 1.5%, p=0.028) and delayed door-to-balloon times for STEMI patients (79 vs 57.5 mins).
Why the study?
During the COVID-19 epidemic, the treatment of patients with acute myocardial infarction (AMI) may have been affected.
Does the COVID-19 epidemic impact the admission volume and treatment times for patients with acute myocardial infarction?
Observational (n=478)
Yes
Does the COVID-19 epidemic impact the admission volume and treatment times for patients with acute myocardial infarction?
Absolute Event Rate: 5% vs 1.5%
p-value: p=0.028
The COVID-19 pandemic was associated with decreased AMI admissions, increased patient refusal of hospitalization, and delayed door-to-balloon times for primary PCI.
Background. At present, COVID-19 is sweeping the world, and all countries are actively responding. During the COVID-19 epidemic, the treatment of patients with acute myocardial infarction (AMI) may be affected. Methods. We reviewed data of patients with AMI from January 23 to April 23, 2020 (2020), and January 23 to April 23, 2019 (2019), who were admitted to two hospitals from Southern China. We collected clinical characteristics, comorbidities, treatment, prognosis, and key time segments to analyze. Results. The total number of patients that had been diagnosed with AMI in the two hospitals was 218 in 2020 and 260 in 2019. The number of AMI patients that were admitted to hospitals per day decreased in 2020. The percentage of patients with AMI who refused hospitalization in 2020 was significantly higher than that in 2019 (5.0% vs 1.5%, <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" id="M1"> <a:mi>p</a:mi> <a:mo>=</a:mo> <a:mn>0.028</a:mn> </a:math> ). There is no statistical difference in symptoms of the first medical contact (S2FMC) time between 2020 and 2019 ( <c:math xmlns:c="http://www.w3.org/1998/Math/MathML" id="M2"> <c:mi>p</c:mi> <c:mo>=</c:mo> <c:mn>0.552</c:mn> </c:math> ). Door-to-balloon (D2B) time of ST-elevation myocardial infarction (STEMI) patients who were treated with a primary percutaneous coronary intervention (pPCI) in 2020 was 79 (63.75–105.25) mins, while D2B time in 2019 was 57.5 (41.5–76.5) mins, which was statistically different from the two groups. Conclusions. COVID-19 had an impact on the number of AMI patients who were admitted to hospitals and the time of treatment. During the COVID-19 epidemic, the number of AMI patients that were admitted to hospitals per day was decreased, while the percentage of AMI patients that refused therapy in these two hospitals increased, and the D2B time of STEMI patients was also delayed.
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Ma et al. (2021) conducted an observational in Acute myocardial infarction (AMI) (n=478). COVID-19 epidemic period (Jan-Apr 2020) vs. Pre-COVID-19 period (Jan-Apr 2019) was evaluated on Refusal of hospitalization among patients with AMI (p=0.028). The COVID-19 epidemic was associated with a higher rate of AMI patients refusing hospitalization (5.0% vs 1.5%, p=0.028) and delayed door-to-balloon times for STEMI patients (79 vs 57.5 mins).
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