Key result
Slow cardiac output kinetics were significantly correlated with skeletal muscle deoxygenation during moderate-intensity exercise in patients with chronic heart failure (rs= -0.57, P=0.005).
Why the study?
Does impaired cardiac output kinetics limit skeletal muscle oxygen delivery during submaximal exercise in patients with chronic heart failure?
Observational (n=43)
Does impaired cardiac output kinetics limit skeletal muscle oxygen delivery during submaximal exercise in patients with chronic heart failure?
Effect estimate: rs= -0.57
p-value: p=0.005
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Central hemodynamics may limit muscle oxygenation during moderate exercise in CHF; leaves open causal role of cardiac output kinetics.
Spee et al. (2016) conducted an observational in Chronic heart failure (n=43). Slow cardiac output kinetics vs. Normal cardiac output kinetics was evaluated on Correlation between cardiac output kinetics (τQ̇) and skeletal muscle deoxygenation (TSImin) (rs= -0.57, p=0.005). Slow cardiac output kinetics were significantly correlated with skeletal muscle deoxygenation during moderate-intensity exercise in patients with chronic heart failure (rs= -0.57, P=0.005).
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