Key result
A constituent-based strain energy function model predicts that biomechanical adaptation maintaining arterial compliance in hypertension is achieved by readjusting the collagen engagement profile alone.
Population
Computational model of arterial remodeling in response to hypertension
Comparison
Constituent-based strain energy function… vs Phenomenological strain energy function models
Authors
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Model prediction of collagen-mediated compliance in hypertension is hypothesis-generating; does not support practice change pending validation.
A novel constituent-based computational model demonstrates that arterial compliance during hypertension can be maintained through readjustment of the collagen engagement profile.
Alkiviadis Tsamis (2007) studied Hypertension. Constituent-based strain energy function (SEF) model vs. Phenomenological SEF models was evaluated on Arterial wall thickening, deformed inner radius, and arterial compliance. A constituent-based strain energy function model predicts that biomechanical adaptation maintaining arterial compliance in hypertension is achieved by readjusting the collagen engagement profile alone.
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