Why the study?
Does Growth Hormone replacement reduce carotid intima-media thickness in adults with GH deficiency?
Population
22 adults with Growth Hormone (GH) deficiency
Comparison
Growth Hormone replacement at a mean dose of 1… vs Baseline values (no separate control group)
Design
Cohort
Follow-up
up to 2 years
Authors
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GH replacement was associated with reduced IMT in GH-deficient adults; leaves open cardiovascular outcome benefit, needs RCTs.
Does Growth Hormone replacement reduce carotid intima-media thickness in adults with GH deficiency?
Growth hormone replacement in adults with GH deficiency significantly reduces carotid intima-media thickness, suggesting a potential direct effect on the arterial wall.
Borson‐Chazot et al. (1999) studied this question.
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