Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 1999Thrombosis and Haemostasis

Circulating Platelets Show Increased Activation in Patients with Acute Cerebral Ischemia

View Full Paper
Ask AI
Bookmark
Share

Population

72 patients with acute cerebral ischemia (ACI) and 72 controls

Design

Case-control

Discussion

Loading...

Member takes

Implication

May inform etiology-specific antiplatelet trials in stroke; hypothesis-generating and should not yet change practice.

Structured PICO

P
Population
72 patients with acute cerebral ischemia (ACI) and 72 controls
C
Comparator
72 controls
O
Outcome
Exposure of activation-dependent adhesion molecules (CD 62, CD 63 and thrombospondin) determined using flow cytometrysurrogate

Platelet activation profiles differ by stroke etiology, with increased activation in atherosclerotic but not cardioembolic acute cerebral ischemia.

Cite This Study

A 1999 study studied this question.

synapsesocial.com/papers/6a82ff21f71f34e1aae8de7ehttps://doi.org/10.1055/s-0037-1614480
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet Activation in the Cerebral Circulation in Different Subtypes of Ischemic Stroke and Binswanger’s Disease1995 · 88 citations
  2. 2Platelet Activation Is Not Involved in Acceleration of the Coagulation System in Acute Cardioembolic Stroke With Nonvalvular Atrial Fibrillation1995 · 35 citations
  3. 3Platelet Activation in Unstable Coronary Disease1986 · 1,149 citations
  4. 4Markers of Hemostatic Activation in Affected Coronary Arteries during Angioplasty1994 · 17 citations
  5. 5Prothrombotic Effects of Erythrocytes on Platelet Reactivity1997 · 125 citations