Genetic determinants of regional fat distribution
Population
Humans (including nuclear families and male identical twins) assessed for obesity-related phenotypes
Design
Review
Authors
Discussion
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Member takes
Implication
Supports genetic basis for regional adiposity; leaves open identification of specific loci before clinical translation.
Structured PICO
P
Population
Humans (including nuclear families and male identical twins) assessed for obesity-related phenotypes
O
Outcome
Heritability and familial transmission of upper body fat and abdominal visceral fat
There is significant genetic heritability for regional fat distribution, justifying the search for specific genes involved in human fat topography.
Cite This Study
Claude Bouchard (1997) studied this question.