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Toxoplasma gondii and Cryptosporidium parvum , members of the phylum Apicomplexa, are significant pathogens of both humans and animals worldwide for which new and effective therapeutics are needed. Here, we describe the activity of the antibiotic boromycin against Toxoplasma and Cryptosporidium . Boromycin potently inhibited intracellular proliferation of both T. gondii and C. parvum at half-maximal effective concentrations (EC 50 ) of 2.27 nM and 4.99 nM, respectively.
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Abenoja et al. (2021) studied this question.
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