December 20, 2001Catheterization and Cardiovascular Interventions
Clinical outcome following percutaneous coronary interventions in patients with chronic renal failure
Why the study?
Does impaired renal function increase mortality in patients undergoing percutaneous coronary intervention?
Population
10,076 consecutive patients who underwent percutaneous coronary intervention between January 1994 and…
Comparison
Percutaneous coronary intervention in patients… vs Percutaneous coronary intervention in patients…
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
Impaired renal function was associated with higher post-PCI mortality; extends prior observations but leaves open whether targeted strategies improve outcomes.
Structured PICO
Does impaired renal function increase mortality in patients undergoing percutaneous coronary intervention?
P
Population
10,076 consecutive patients who underwent percutaneous coronary intervention between January 1994 and December 1997, stratified by renal function (95 ESRD on dialysis, 786 CRF, 9,125 normal renal function).
I
Intervention
Percutaneous coronary intervention (PCI) in patients with chronic renal failure or end-stage renal disease on dialysis
C
Comparator
Percutaneous coronary intervention (PCI) in patients with normal renal function
O
Outcome
In-hospital mortality and 1-year mortalityhard clinical
Impaired renal function, particularly end-stage renal disease, is a strong independent predictor of both in-hospital and 1-year mortality following percutaneous coronary intervention.
Cite This Study
Gruberg et al. (2001) studied this question.