September 1, 1951CirculationOpen Access

The Effect of Intravenously Administered Digoxin on Water and Electrolyte Excretion and on Renal Functions

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Why the study?

Does intravenously administered digoxin increase water and electrolyte excretion in patients with congestive heart failure?

Population

Patients with congestive heart failure, patients with noncardiac edema, and patients without edema

Design

Other

Authors

SFSaul J. FärberUniversity of Washington JAJohn D. AlexanderUniversity of Vermont EPEdmund D. PellegrinoUniversity of New Haven

Discussion

Member takes

Implication

Hypothesis-generating for digoxin diuresis in HF; leaves open relevance versus contemporary therapies.

Structured PICO

Does intravenously administered digoxin increase water and electrolyte excretion in patients with congestive heart failure?

Population

Patients with congestive heart failure, patients with noncardiac edema, and patients without edema

Intervention

Intravenously administered digoxin

Outcome

Water and electrolyte excretion (salt/sodium diuresis) and renal functions (renal hemodynamics, glomerular filtration rate)surrogate

Intravenous digoxin induces significant diuresis in heart failure patients, primarily associated with decreased venous pressure rather than changes in renal hemodynamics.

Cite This Study

Färber et al. (1951) studied this question.

synapsesocial.com/papers/6a831764f568d6f39593caae https://doi.org/10.1161/01.cir.4.3.378

View Full Paper

Ask AI

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The Effect of Intravenously Administered Digoxin on Water and Electrolyte Excretion and on Renal Functions

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Effect of Intravenously Administered Digoxin on Water and Electrolyte Excretion and on Renal Functions

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider