September 1, 1993Proceedings of the National Academy of SciencesOpen Access

Development of polyclonal antibodies against angiotensin type 2 receptors.

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Population

Murine neuroblastoma N1E-115 cells and a kidney epithelial cell line

Design

Preclinical

Authors

LRLawrence P. ReaganUniversity of South Carolina XYXiaodong YangTongji University ISIvo R. SiemensNew Frontier

Discussion

Member takes

Implication

May aid AT2 receptor characterization in research models; leaves open translation to human cardiovascular applications.

Structured PICO

Population

Murine neuroblastoma N1E-115 cells and a kidney epithelial cell line

Intervention

Development of protein-directed polyclonal antibodies using partially purified solubilized N1E-115 membranes enriched for AT2 receptors

Outcome

Specificity and immunoreactivity of the developed antibodies against AT2 receptorssurrogate

The study successfully developed specific polyclonal antibodies against the AT2 receptor, providing a tool for further cellular and molecular characterization of this receptor subtype.

Cite This Study

Reagan et al. (1993) studied this question.

synapsesocial.com/papers/6a83193e103ff40a2293c4be https://doi.org/10.1073/pnas.90.17.7956

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Development of polyclonal antibodies against angiotensin type 2 receptors.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Development of polyclonal antibodies against angiotensin type 2 receptors.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider