Why the study?
Carney complex is a rare autosomal dominant disorder where cardiac tumours are the leading cause of death, requiring challenging diagnosis and regular screening to prevent sudden cardiac death and embolic events.
Case Report (n=1)
This case highlights the importance of recognizing Carney complex in patients with characteristic lentiginosis and endocrine tumors to enable early screening and prevention of cardioembolic events from cardiac myxomas.
May aid early Carney complex identification to avert cardioembolic risks; leaves open validation in larger cohorts.
The Carney complex (CNC) is a rare autosomal dominant genetic complex that is characterised by multiple neoplasms consisting of neuroendocrine and cardiac tumours, with only 750 cases reported worldwide as of 2017. Cardiac tumours, in the context of the CNC, are of unique importance since the leading causes of death in patients with CNC are cardiac. To prevent sudden cardiac death and embolic events, a difficult diagnosis must be made and postdiagnostic screenings must be regular. We present a case of a 52-year-old man, with a medical history of pituitary microadenoma and facial lentiginosis, who presented with dyspnoea 2 months after suffering a cerebrovascular accident.
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Spindel et al. (2021) conducted a case report in Carney complex (n=1). Surgical resection of left atrial myxoma was evaluated.
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