Why the study?
Do increased free fatty acids inhibit glucose-stimulated glucose transport and phosphorylation in healthy men?
Population
7 healthy men
Comparison
Increased plasma free fatty acid concentrations… vs Low plasma FFA concentrations during…
Design
Other
Follow-up
300 minutes
Authors
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Hypothesis-generating for FFA effects on muscle glucose uptake; leaves open relevance to insulin resistance or hyperglycemia in patients.
Do increased free fatty acids inhibit glucose-stimulated glucose transport and phosphorylation in healthy men?
Increased free fatty acids directly inhibit glucose transport and phosphorylation in skeletal muscle, supporting Randle's hypothesis.
Krebs et al. (2001) studied this question.
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