Developed a structurally-motivated constitutive law using three coefficients to accurately predict the stress-strain behavior of aortic valve leaflets, which can be applied to computational modeling for clinical and engineering valve treatments.
May aid computational valve simulations; leaves open human translation pending validation.
The objective of the present study was to perform biaxial testing and apply constitutive modeling to develop a strain energy function that accurately predicts the material behavior of the aortic valve leaflets. Ten leaflets from seven normal porcine aortic valves were biaxially stretched in a variety of protocols and the data combined to develop and fit a strain energy function to describe the material behavior. The results showed that the nonlinear anisotropic behavior of the aortic valve is well described by a strain energy function of two strain invariants, which uses only three coefficients to accurately predict the stress-strain behavior over a wide range of deformations. This structurally-motivated constitutive law has many applications, including computational modeling for clinical and engineering valve treatments.
No takes yet. Share an insight, caveat, or question.
May‐Newman et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: